Abstract: Based on assessment theories and quantitative evaluation methods of cloud water resources, using ERA5 high-resolution reanalysis data and gridded observed precipitation data, we analyze and evaluate the characteristics and changing trends of cloud water resources in Anhui province from 2000 to 2021. Results reveal the following: (1) The spatial horizontal distributions of mean state of water vapor (Water vapor content), mean state of hydrometeor (hydrometeor content), precipitation (Ps) in Anhui province are zonal, and the values decrease with increasing latitude. In summer, the hydrometeors are mainly distributed in the middle layer (between 600 and 350 hPa). The hydrometeors in spring, autumn, and winter are mainly below 500 hPa. (2) The water vapor advection transport are showed convergence between 900 and 450 hPa, while the hydrometeor are showed convergence between 850 and 600 hPa. The intensity of water vapor advection transport in summer is significantly higher than in other seasons, with the peak appearing between 850 and 700 hPa. In the advection transport of hydrometeors, there is hydrometeor net input approximately 700 hPa in winter, and between 600 and 500 hPa in autumn. The water vapor and hydrometeors budget at the western boundary and northern boundary show an increasing trend, while at the southern boundary and eastern boundary show an decreasing trend. (3) The annual total amount of atmospheric hydrometeor (GMh) in Anhui province is approximately 2281.2 mm, and the precipitation efficiency of hydrometeor (PEh) is 56%. The cloud water resource (CWR) is 995.9 mm, and the CWR in Anhui province shows a slow increasing trend from 2000 to 2021. The variable of cloud condensation (Cvh) is also high and low in the more-rain years and less-rain years, respectively. The monthly variations in GMh, the gross mass of water vapor (GMv), Ps, PEh, and CWR show a single peak distribution. The results are helpful for understanding the characteristics of CWR and providing some beneficial reference for enhancing the efficiency of CWR development in Anhui province.