Abstract: The Shenzhen National Climate Observatory is the only national-level climate observatory in the Pearl River Delta Economic Circle in China. After more than 20 years of continuous development, it possesses various capabilities, including comparative monitoring of urban and suburban climate conditions, joint monitoring of meteorology and atmospheric environment, three-dimensional monitoring of atmospheric conditions from ground to upper-level air, and collaborative monitoring of climate patterns over land and ocean. Based on the observation data obtained from the observatory, scholars in atmospheric science have conducted successful research with fruitful results in multiple fields such as urban climate, boundary layer physics, atmospheric environment and environmental meteorology, climate resources, and lightning characteristics in the Guangdong–Hong Kong–Macao Greater Bay Area, further enriching the scientific understanding in these fields. In addition, the observatory supports local disaster prevention and reduction, urban management, urban planning, and ecological civilization construction in Shenzhen, thereby serving as a model for leveraging the social benefits of meteorological observation.