Abstract: The evolution patterns and driving mechanisms of monsoon systems are extensively studied. Geological records provide key insights into the dominant factors controlling multiscale monsoon variability. Previous studies have primarily reviewed paleomonsoon variations based on paleoclimate reconstructions. In recent years, the spatiotemporal characteristics and underlying mechanisms of multiscale paleomonsoon changes have been elucidated in detail owing to advances in Earth system modeling. However, systematic modeling studies on paleomonsoon multitimescale variability are lacking. Therefore, recent paleoclimate modeling studies are reviewed herein, and their key findings and advances in global monsoon variability across orbital, millennial, centennial, and decadal timescales since the late Quaternary are reported. Furthermore, future research priorities, including investigations into cross-timescale interactions, tipping points in monsoon systems, and the development and application of Earth system models, paleoclimate data assimilation, and machine learning methods, are highlighted. These efforts will facilitate a better understanding of global monsoon multiscale variability and improve the projections of future monsoon changes.